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An endometrial biopsy involves taking a small sample of cells from the lining of your uterus (womb). This can be slightly uncomfortable and feel like a cramping pain similar to a period. For the majority of women this only lasts for a few seconds and settles quickly. Following the sample, you may have a small amount of vaginal bleeding or spotting. This usually settles within a day or two. You can take simple pain relief like paracetamol or ibuprofen for any discomfort experienced after the procedure. We will write to you and your GP with the result of the sample when available (provided you have given us permission to do so). Very occasionally the sample does not collect enough tissue and the procedure needs repeated. Should you experience heavy bleeding, significant abdominal pain, fever or abnormal discharge after the procedure please ask for medical advice, either from your GP or one of the contacts below: Sandyford Nurse Helpline Mon – Fri from 8.30am - 4.30pm Call 0141 211 8130 and ask to be put through to a nurse Call 111